Sweden

Stockholm Medical Biobank (SMB)

Stockholm Medical Biobank coordinates, facilitates and streamlines biobank work in the region and serves as a central resource for the collection, storage, facilitation and use of joint Biobank samples.

More than 6 million samples are handled annually.

Key facts

Name of the connected EIT Health partner: Region Stockholm
Number of individuals: Total ~500,000
Biobank confirmed willingness to provide samples/data for EIT Health studies: SMB contains a large number of sample collections and are the only biobank with Region Stockholm as principal. The biobank has sample collections containing samples saved primarily for health and medical care as well as samples saved primarily for research. Samples saved for health and medical care can also be used for research, after approval from the Swedish Ethical Review Authority and permission from the biobank custodian.
Contact person(s) and contact data
(e-mail address, tel. no) for access purposes:
biobankstockholm.lsf@sll.se   Tel: 08-517 725 52, Region Stockholm´s biobank coordinator and head of Stockholm’s medicinal biobank: Lena Brynne, lena.brynne@sll.se
Number of samples: Total >20 million
Sample type: Various types
Website: Stockholm Medical Biobank

General information

Type of biobank: SMB has the responsibility for biobank samples from the healthcare in the region of Stockholm. The region’s former biobanks are now converted into sample collections or biobank departments under the SMB.
If longitudinal the frequency: Not available.
Broad consent: Consent to save samples for future research can be broad. But Ethical consent in Sweden is rarely broad, and almost always linked to specific disease areas. Consent to participate in a study should always be informed and specified according to GDPR. A new approval from the Ethics Review Authority in Sweden is needed for each new study. They also assess whether the study can be covered by the already obtained consent or if new consent needs to be obtained.
Option to recall donors: Not available.
Option to recall family members: Not available.

Biobank access procedure:

Major terms for access: Samples can be made available to research groups and companies after consent and a decision from the Swedish ethical review authority and after application to biobank custodian.
Ethical and legal compliance: Rules for access to biobank samples can be found at www.biobanksverige.se  https://biobanksverige.se/english/research/getting-started/principles-of-access/      
Speed and reliability of delivery: Not available.
Pricing: Not available.

Quality management system:

Link to operational procedure: Quality management system used in healthcare within the relevant laboratory.
Storage: Not available.
Compliance with international standards: Not available.
Current ISO certificates: Not available.

Data:

Clinical data linked to samples: This varies in different sample collections.
Data standards: Differs between sample collections
Data security rules: Differs between sample collections

Biobank related service:

Research support, what type of expertise?: Services and guidance to academic research groups, industry and health care. Applications for sample collection agreements. Regulatory biobank service. Operational biobank service.
Core facility services; what type? Link?: https://biobankstockholm.se/sites/biobank.sll.se/
files/documents/informationsblad_om_smb.pdf
Queries from national health registers: Not available.
Links to the model contract and MTA: https://biobanksverige.se/english/research/useful-resources/application-form-selector/

IP:

IP rules, what is negotiable?: Must be handled per sample collection.
Requirements to study results (access etc.): Must be handled per sample collection.
Participant’s right to the information: Must be handled per sample collection.

COVID-19 samples:

Access to biological samples from patients with COVID-19?

  • Serum
  • Full blood (for RNA extraction)
  • EDTA-Full blood (for DNA extraction)
  • EDTA-Plasma
  • Citrate-Plasma
  • PBMC (Peripheral Blood Mononuclear Cells)
  • Nasopharyngeal aspirate
  • Tracheal aspirate
Must be handled per sample collection.
Contact person(s) and contact data for access purposes biobankstockholm.lsf@sll.se

The "Registers and Biobanks in Transition” strategic initiative is funded by EIT Health